Description
PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48.
Product information
CAS Number: 1180676-33-8
Molecular Weight: 286.75
Formula: C17H15ClO2
Chemical Name: (2E)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid
Smiles: OC(=O)/C=C(\CCC1C=CC(Cl)=CC=1)/C1C=CC=CC=1
InChiKey: LLJYFDRQFPQGNY-NTCAYCPXSA-N
InChi: InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (348.74 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PS47 shows very low binding affinity or no binding to PDK1 (Kd>200 µM).
Products are for research use only. Not for human use.
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