Boc-C1-PEG3-C4-OH


Catalog No. Size PriceQuantity
M14342-2 2mg solid $90
M14342-10 10mg solid $270

Description

Boc-C1-PEG3-C4-OH is a PROTAC linker, which refers to the Alkyl/ether composition. Boc-C1-PEG3-C4-OH can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Product information

CAS Number: 2376724-97-7

Molecular Weight: 320.42

Formula: C16H32O6

Chemical Name: tert-butyl 2-(2-{2-[(6-hydroxyhexyl)oxy]ethoxy}ethoxy)acetate

Smiles: CC(C)(C)OC(=O)COCCOCCOCCCCCCO

InChiKey: RFJQECXXHSDFPN-UHFFFAOYSA-N

InChi: InChI=1S/C16H32O6/c1-16(2,3)22-15(18)14-21-13-12-20-11-10-19-9-7-5-4-6-8-17/h17H,4-14H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

Products are for research use only. Not for human use.

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