Description
1,2,3,4,5,6-Hexabromocyclohexane (NSC7908) is a potent inhibitor of JAK2 tyrosine kinase autophosphorylation with IC50 value to be estimated in low micromolar range.
Product information
CAS Number: 1837-91-8
Molecular Weight: 557.54
Formula: C6H6Br6
Chemical Name: 1,2,3,4,5,6-hexabromocyclohexane
Smiles: BrC1C(Br)C(Br)C(Br)C(Br)C1Br
InChiKey: QFQZKISCBJKVHI-UHFFFAOYSA-N
InChi: InChI=1S/C6H6Br6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-6H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Solubility (25°C). 5 mg/mL(8.96 mM). Insoluble.
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
1,2,3,4,5,6-Hexabromocyclohexane inhibits Jak2 autophosphorylation in a time- and dose-dependent manner. 1,2,3,4,5,6-Hexabromocyclohexane is noncytotoxic to cells at concentrations that maximally inhibit Jak2 tyrosine autophosphorylation.
Products are for research use only. Not for human use.
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