DMX-5084


Catalog No. Size PriceQuantity
M14481-2 Contact sales@xcessbio.com for quotation $100

Description

DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.

Product information

CAS Number: 2306178-56-1

Molecular Weight: 361.39

Formula: C21H19N3O3

Chemical Name: 5-[4-(2-methoxyethoxy)phenyl]-7-phenyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one

Smiles: COCCOC1C=CC(=CC=1)C1=CN(C2N=CNC(=O)C1=2)C1C=CC=CC=1

InChiKey: FUSHFOGORKZNNQ-UHFFFAOYSA-N

InChi: InChI=1S/C21H19N3O3/c1-26-11-12-27-17-9-7-15(8-10-17)18-13-24(16-5-3-2-4-6-16)20-19(18)21(25)23-14-22-20/h2-10,13-14H,11-12H2,1H3,(H,22,23,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 72 mg/mL(199.23 mM). Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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