Description
3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway.
Product information
CAS Number: 53350-26-8
Molecular Weight: 372.37
Formula: C20H20O7
Chemical Name: 5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one
Smiles: COC1=CC(=CC(OC)=C1OC)C1=CC(=O)C2C(=CC(=CC=2OC)OC)O1
InChiKey: GIKVSFNAEBQLGB-UHFFFAOYSA-N
InChi: InChI=1S/C20H20O7/c1-22-12-8-15(23-2)19-13(21)10-14(27-16(19)9-12)11-6-17(24-3)20(26-5)18(7-11)25-4/h6-10H,1-5H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Hou X, et al. 3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. Mol Cells. 2015 May;38(5):396-401.
Products are for research use only. Not for human use.
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