Description
beta-L-D4A is a nucleoside HIV-1 reverse transcriptase inhibitor.
Product information
CAS Number: 7057-48-9
Molecular Weight: 233.23
Formula: C10H11N5O2
Synonym:
2'3'-didehydro-2'3'-dideoxyadenosine
Chemical Name: [(2S,5R)-5-(6-amino-9H-purin-9-yl)-2,5-dihydrofuran-2-yl]methanol
Smiles: NC1N=CN=C2C=1N=CN2[C@H]1C=C[C@@H](CO)O1
InChiKey: JFUOUIPRAAGUGF-NKWVEPMBSA-N
InChi: InChI=1S/C10H11N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h1-2,4-7,16H,3H2,(H2,11,12,13)/t6-,7+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
beta-L-D4A is a nucleoside HIV-1 reverse transcriptase inhibitor. Results confirm that the biological activity of NSC 108602 is connected with the termination of the DNA chain synthesis in the 5′-3′ direction.
References:
- Ponomareva AG, et al. Structural and energetic properties of the potential HIV-1 reverse transcriptase inhibitors d4A and d4G: a comprehensive theoretical investigation. J Biomol Struct Dyn. 2014;32(5):730-40.
Products are for research use only. Not for human use.
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