p-Coumaric Acid


Catalog No. Size PriceQuantity
M14738-2 Contact sales@xcessbio.com for quotation $100

Description

p-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.

Product information

CAS Number: 501-98-4

Molecular Weight: 164.16

Formula: C9H8O3

Synonym:

trans-4-Hydroxycinnamic acid

Chemical Name: 3-(4-hydroxyphenyl)prop-2-enoic acid

Smiles: OC1C=CC(=CC=1)C=CC(O)=O

InChiKey: NGSWKAQJJWESNS-ZZXKWVIFSA-N

InChi: InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 32 mg/mL(194.93 mM). Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

p-Coumaric acid is the most abundant isomer in natureand is biosynthesized from cinnamic acid by the action ofthe P450-dependent enzyme 4-cinnamic acid hydroxylase. p-Coumaric acid possesses antioxidant properties that reduce the risk of stomachcancer by suppressing the formation of carcinogenic nitrosamines. p-coumaric acid effectively suppressed endo-thelial cell migration, tube formation, and rat aorta ring sprouting. It reduces intracellular andmitochondrial reactive oxygen species production.

In Vivo:

p-coumaric acid signif-icantly suppressed tumor growth in vivo by blockingangiogenesis.

Products are for research use only. Not for human use.

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