GSK9311 hydrochloride


Catalog No. Size PriceQuantity
M14810-2 Contact sales@xcessbio.com for quotation $100

Description

GSK9311 hydrochloride, a less active analogue of GSK6853, can be used as a negative control. GSK9311 hydrochloride inhibits BRPF bromodomain with pIC50 values of 6.0 and 4.3 for BRPF1 and BRPF2, respectively.

Product information

CAS Number: 2253733-09-2

Molecular Weight: 474.00

Formula: C24H32ClN5O3

Chemical Name: N-{1,3-dimethyl-6-[(2R)-2-methylpiperazin-1-yl]-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl}-N-ethyl-2-methoxybenzamide; chlorohydrogen

Smiles: Cl.CCN(C(=O)C1=CC=CC=C1OC)C1C=C2C(=CC=1N1CCNC[C@H]1C)N(C)C(=O)N2C

InChiKey: WMVWXTNJPAEJEN-PKLMIRHRSA-N

InChi: InChI=1S/C24H31N5O3.ClH/c1-6-28(23(30)17-9-7-8-10-22(17)32-5)20-13-18-19(27(4)24(31)26(18)3)14-21(20)29-12-11-25-15-16(29)2;/h7-10,13-14,16,25H,6,11-12,15H2,1-5H3;1H/t16-;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain, and demonstrates properties suitable for cellular and in vivo studies. GSK6853 is a less active analogue of GSK6853 in which the 5-amide is alkylated.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed