Description
Rosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice .
Product information
CAS Number: 84954-93-8
Molecular Weight: 428.43
Formula: C20H28O10
Chemical Name: (2R,3S,4S,5R,6R)-2-({[(2R,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-6-{[(2E)-3-phenylprop-2-en-1-yl]oxy}oxane-3,4,5-triol
Smiles: OC[C@@H]1O[C@@H](OC[C@H]2O[C@@H](OC/C=C/C3C=CC=CC=3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O
InChiKey: IEBFEMIXXHIISM-YZOUKVLTSA-N
InChi: InChI=1S/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Rosarin (0-50 μg/ml; 18 hours) pretreats 30 mins in LPS-induced BV-2 cells supresses iNOS and cytokines expression in a concentration-dependent manner in the murine BV2 cells.
Products are for research use only. Not for human use.
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