Liproxstatin-1 hydrochloride


Catalog No. Size PriceQuantity
M15002-2 Contact sales@xcessbio.com for quotation $100

Description

Liproxstatin-1 hydrochloride is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM).

Product information

CAS Number: 2250025-95-5

Molecular Weight: 377.31

Formula: C19H22Cl2N4

Chemical Name: N-[(3-chlorophenyl)methyl]-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine; chlorohydrogen

Smiles: Cl.ClC1=CC(CNC2=NC3C=CC=CC=3NC32CCNCC3)=CC=C1

InChiKey: HEHOHTKMIOBTKC-UHFFFAOYSA-N

InChi: InChI=1S/C19H21ClN4.ClH/c20-15-5-3-4-14(12-15)13-22-18-19(8-10-21-11-9-19)24-17-7-2-1-6-16(17)23-18;/h1-7,12,21,24H,8-11,13H2,(H,22,23);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Liproxstatin-1 shows antiferroptotic activity with an IC50 of approximately 38 nM in mouse embryonic fibroblasts.

In Vivo:

Liproxstatin-1 (10 mg/kg, i.p.) suppresses ferroptosis in human cells, Gpx4-/- kidney and in an ischaemia/reperfusion-induced tissue injury model.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed