Bisdionin C


Catalog No. Size PriceQuantity
M15184-2 Contact sales@xcessbio.com for quotation $100

Description

Bisdionin C is a potent GH18 chitinases inhibitor, with an IC50 of 0.2 μM for A. fumigatus ChiB1 (AfChiB1). Bisdionin C inhibits HCHT (human macrophage chitotriosidase) and acidic mammalian chitinase (AMCase) with IC50s of 8.3 and 3.4 μM, respectively.

Product information

CAS Number: 74857-22-0

Molecular Weight: 400.39

Formula: C17H20N8O4

Chemical Name: 1-[3-(3,7-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)propyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

Smiles: CN1C=NC2=C1C(=O)N(CCCN1C(=O)N(C)C3N=CN(C)C=3C1=O)C(=O)N2C

InChiKey: KEPIKAFUZRKZMT-UHFFFAOYSA-N

InChi: InChI=1S/C17H20N8O4/c1-20-8-18-12-10(20)14(26)24(16(28)22(12)3)6-5-7-25-15(27)11-13(19-9-21(11)2)23(4)17(25)29/h8-9H,5-7H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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