Description
4-CMTB is a selective free fatty acid receptor 2 (FFA2/GPR43) agonist and a positive allosteric modulator (pEC50=6.38).
Product information
CAS Number: 300851-67-6
Molecular Weight: 294.80
Formula: C14H15ClN2OS
Chemical Name: 2-(4-chlorophenyl)-3-methyl-N-(1,3-thiazol-2-yl)butanamide
Smiles: CC(C)C(C(=O)NC1=NC=CS1)C1=CC=C(Cl)C=C1
InChiKey: AZYDQCGCBQYFSE-UHFFFAOYSA-N
InChi: InChI=1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (339.21 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
4-CMTB is both a direct agonist and a positive allosteric modulator of the action of short-chain free fatty acids. 4-CMTB modulates the activity of short-chain fatty acids at FFA2 via the FFA2 second extracellular loop (ECL2).
Products are for research use only. Not for human use.
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