Description
PK150 is an analogue of Sorafenib and shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 is an inhibitor of Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA) and Vancomycin intermediate S. aureus (VISA) with MIC of 0.3 µM, 0.3-1 µM and 0.3 µM, respectively.
Product information
CAS Number: 2165324-62-7
Molecular Weight: 394.68
Formula: C15H8ClF5N2O3
Chemical Name: 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)urea
Smiles: O=C(NC1=CC(=C(Cl)C=C1)C(F)(F)F)NC1=CC2OC(F)(F)OC=2C=C1
InChiKey: SHPYXCLUNMOJOB-UHFFFAOYSA-N
InChi: InChI=1S/C15H8ClF5N2O3/c16-10-3-1-7(5-9(10)14(17,18)19)22-13(24)23-8-2-4-11-12(6-8)26-15(20,21)25-11/h1-6H,(H2,22,23,24)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Solubility (25°C).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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