GSK2292767


Catalog No. Size PriceQuantity
M15442-2 Contact sales@xcessbio.com for quotation $100

Description

GSK2292767 is a potent and selective PI3Kδ inhibitor.

Product information

CAS Number: 1254036-66-2

Molecular Weight: 512.58

Formula: C24H28N6O5S

Chemical Name: N-[5-(4-{5-[(2,6-dimethylmorpholin-4-yl)methyl]-1,3-oxazol-2-yl}-1H-indazol-6-yl)-2-methoxypyridin-3-yl]methanesulfonamide

Smiles: COC1N=CC(=CC=1NS(C)(=O)=O)C1=CC2NN=CC=2C(=C1)C1=NC=C(CN2CC(C)OC(C)C2)O1

InChiKey: NLUPPCTVKHDVIQ-UHFFFAOYSA-N

InChi: InChI=1S/C24H28N6O5S/c1-14-11-30(12-15(2)34-14)13-18-9-26-23(35-18)19-5-16(6-21-20(19)10-27-28-21)17-7-22(29-36(4,31)32)24(33-3)25-8-17/h5-10,14-15,29H,11-13H2,1-4H3,(H,27,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 100 mg/mL(195.09 mM). Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

GSK2292767 is highly selective for PI3Kδ over the closely related isoforms and is active in a disease relevant brown Norway rat acute OVA model of Th2-driven lung inflammation.

Products are for research use only. Not for human use.

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