Description
Bis-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 96517-92-9
Molecular Weight: 250.25
Formula: C10H18O7
Chemical Name: 3-{2-[2-(2-carboxyethoxy)ethoxy]ethoxy}propanoic acid
Smiles: OC(=O)CCOCCOCCOCCC(O)=O
InChiKey: WFLUHYUKINZPNZ-UHFFFAOYSA-N
InChi: InChI=1S/C10H18O7/c11-9(12)1-3-15-5-7-17-8-6-16-4-2-10(13)14/h1-8H2,(H,11,12)(H,13,14)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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