Description
Palbociclib D8 (PD 0332991 D8) is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib has the potential for ER-positive and HER2-negative breast cancer research.
Product information
CAS Number: 1628752-83-9
Molecular Weight: 455.58
Formula: C24H29N7O2
Chemical Name: 6-acetyl-8-cyclopentyl-5-methyl-2-({5-[(2,2,3,3,5,5,6,6-²H₈)piperazin-1-yl]pyridin-2-yl}amino)-7H,8H-pyrido[2,3-d]pyrimidin-7-one
Smiles: [2H]C1([2H])NC([2H])([2H])C([2H])([2H])N(C2=CN=C(C=C2)NC2N=C3C(=CN=2)C(C)=C(C(=O)N3C2CCCC2)C(C)=O)C1([2H])[2H]
InChiKey: AHJRHEGDXFFMBM-PMCMNDOISA-N
InChi: InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)/i9D2,10D2,11D2,12D2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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