Description
AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1, with IC50s of 0.885 and 2.03 nM for human and mouse AhR.
Product information
CAS Number: 2338747-54-7
Molecular Weight: 418.37
Formula: C20H17F3N4O3
Chemical Name: N-[(2S)-1-hydroxypropan-2-yl]-2-(pyridin-3-yl)-6-[4-(trifluoromethoxy)phenyl]pyrimidine-4-carboxamide
Smiles: C[C@@H](CO)NC(=O)C1C=C(N=C(N=1)C1C=NC=CC=1)C1C=CC(=CC=1)OC(F)(F)F
InChiKey: CSSGBPKFVJOAIZ-LBPRGKRZSA-N
InChi: InChI=1S/C20H17F3N4O3/c1-12(11-28)25-19(29)17-9-16(26-18(27-17)14-3-2-8-24-10-14)13-4-6-15(7-5-13)30-20(21,22)23/h2-10,12,28H,11H2,1H3,(H,25,29)/t12-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 250 mg/mL (597.56 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
