AZ2


Catalog No. Size PriceQuantity
M15789-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

AZ2 is a highly selective PI3Kγ inhibitor (The pIC50 value for PI3Kγ is 9.3). AZ2 can be used for the research of inflammatory and immune diseases.

Product information

CAS Number: 2231760-33-9

Molecular Weight: 369.48

Formula: C20H23N3O2S

Chemical Name: N-(5-{2-[(1S)-1-cyclopropylethyl]-7-methyl-1-oxo-2, 3-dihydro-1H-isoindol-5-yl}-4-methyl-1, 3-thiazol-2-yl)acetamide

Smiles: C[C@@H](C1CC1)N1CC2=CC(=CC(C)=C2C1=O)C1SC(NC(C)=O)=NC=1C

InChiKey: CNCRCDLWUGCPSJ-LBPRGKRZSA-N

InChi: InChI=1S/C20H23N3O2S/c1-10-7-15(18-11(2)21-20(26-18)22-13(4)24)8-16-9-23(19(25)17(10)16)12(3)14-5-6-14/h7-8,12,14H,5-6,9H2,1-4H3,(H,21,22,24)/t12-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

AZ2 (0.1~100 nM; 1 hour; SKOV-3 cells) excellent selectivity for PI3Kγ is further confirmed with a constitutively activated PI3K/Akt pathway.

Products are for research use only. Not for human use.

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