Andrograpanin


Catalog No. Size PriceQuantity
M15923-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties.

Product information

CAS Number: 82209-74-3

Molecular Weight: 318.45

Formula: C20H30O3

Chemical Name: 3-{2-[(1R, 4aS, 5R, 8aS)-5-(hydroxymethyl)-5, 8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethyl}-2, 5-dihydrofuran-2-one

Smiles: C[C@@]12CCC[C@@](C)(CO)[C@H]1CCC(=C)[C@H]2CCC1=CCOC1=O

InChiKey: WKKBRRFSRMDTJB-JYBIWHBTSA-N

InChi: InChI=1S/C20H30O3/c1-14-5-8-17-19(2,13-21)10-4-11-20(17,3)16(14)7-6-15-9-12-23-18(15)22/h9,16-17,21H,1,4-8,10-13H2,2-3H3/t16-,17-,19+,20+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways. Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells.

Products are for research use only. Not for human use.

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