6-Hydroxy-DOPA


Catalog No. Size PriceQuantity
M15991-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer.

Product information

CAS Number: 21373-30-8

Molecular Weight: 213.19

Formula: C9H11NO5

Chemical Name: 2-amino-3-(2,4,5-trihydroxyphenyl)propanoic acid

Smiles: NC(CC1=CC(O)=C(O)C=C1O)C(O)=O

InChiKey: YLKRUSPZOTYMAT-UHFFFAOYSA-N

InChi: InChI=1S/C9H11NO5/c10-5(9(14)15)1-4-2-7(12)8(13)3-6(4)11/h2-3,5,11-13H,1,10H2,(H,14,15)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

6-Hydroxy-DOPA (0~20 μM; U20S cells) selectively inhibits RAD52-mediated recombination. 6-Hydroxy-DOPA (0~10 μM; HEK293T cells) decreases the number of eGFP-RAD52 foci in a dose-dependent manner. 6-Hydroxy-DOPA (5~75 μM; HCC1937 cells) selectively reduces the viability of the BRCA1-deficient triple-negative breast cancer cell line HCC1937.

Products are for research use only. Not for human use.

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