Description
(-)-Integerrimine, a pyrrolizidine alkaloid, has antiulcerogenic activity. (-)-Integerrimine is also a mutagenic and weakly clastogenic agent in Drosophila.
Product information
CAS Number: 480-79-5
Molecular Weight: 335.39
Formula: C18H25NO5
Chemical Name: (1R, 4E, 6R, 7R, 17R)-4-ethylidene-7-hydroxy-6, 7-dimethyl-2, 9-dioxa-14-azatricyclo[9.5.1.0, ]heptadec-11-ene-3, 8-dione
Smiles: C[C@@H]1C/C(=C\C)/C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@]1(C)O)[C@@H]32
InChiKey: HKODIGSRFALUTA-IKZAEVNJSA-N
InChi: InChI=1S/C18H25NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,11,14-15,22H,6-10H2,1-3H3/b12-4+/t11-,14-,15-,18-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
(-)-Integerrimine (0.00625-0.05 mM) also must have mutagenic activity in somatic cells of Drosophila. (-)-Integerrimine in general requires cytochrome P450-dependent metabolic activation to exhibit genotoxic activity.
Products are for research use only. Not for human use.
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