2', 3'-cGAMP-C2-SH

2',3'-cGAMP-C2-SH is a ADC cytotoxin that is extracted from patent US20210015941, example 24.

Product information

CAS Number: 2133823-39-7

Molecular Weight: 718.53

Formula: C22H28N10O12P2S

Chemical Name: (1R,6R,8R,9R,10S,15S,17R,18R)-17-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-8-(6-amino-9H-purin-9-yl)-3,9,12-trihydroxy-18-(2-sulfanylethyl)-2,4,7,11,13,16-hexaoxa-3λ⁵,12λ⁵-diphosphatricyclo[13.2.1.0⁶,¹⁰]octadecane-3,12-dione

Smiles: NC1NC2=C(N=CN2[C@@H]2O[C@@H]3COP(O)(=O)O[C@@H]4[C@@H](COP(O)(=O)O[C@@H]2[C@@H]3CCS)O[C@H]([C@@H]4O)N2C=NC3=C2N=CN=C3N)C(=O)N=1

InChiKey: WKFFSEOIKYTXCF-TUUUSIAGSA-N

InChi: InChI=1S/C22H28N10O12P2S/c23-16-11-17(26-5-25-16)31(6-27-11)20-13(33)15-10(42-20)4-40-45(35,36)43-14-8(1-2-47)9(3-39-46(37,38)44-15)41-21(14)32-7-28-12-18(32)29-22(24)30-19(12)34/h5-10,13-15,20-21,33,47H,1-4H2,(H,35,36)(H,37,38)(H2,23,25,26)(H3,24,29,30,34)/t8-,9-,10-,13-,14-,15-,20-,21-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

2',3'-cGAMP-C2-SH is a toxin molecule that can be used to synthesize ADCs.

Products are for research use only. Not for human use.