Description
Hepln-13 is a potent and orally active Hepsin inhibitor with an IC50 of 0.33 µM. Hepln-13 can be used for the research of metastatic prostate cancer.
Product information
CAS Number: 64369-13-7
Molecular Weight: 325.20
Formula: C17H13BrN2
Chemical Name: 2-(4-bromophenyl)-2,3-dihydro-1H-perimidine
Smiles: BrC1C=CC(=CC=1)C1NC2C=CC=C3C=CC=C(N1)C3=2
InChiKey: YSRRRCGJBGQBDM-UHFFFAOYSA-N
InChi: InChI=1S/C17H13BrN2/c18-13-9-7-12(8-10-13)17-19-14-5-1-3-11-4-2-6-15(20-17)16(11)14/h1-10,17,19-20H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Hepln-13 (10 µM; 2 hours; 293 cells) inhibits cleavage.
In Vivo:
HepIn-13 displays dose dependent inhibition of Hepsin overexpression-relevant prostate cancer phenotypes and blocks prostate cancer metastasis.
Products are for research use only. Not for human use.
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