Lipoamide-PEG3-Mal


Catalog No. Size PriceQuantity
M16508-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Lipoamide-PEG3-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1314378-19-2

Molecular Weight: 559.74

Formula: C25H41N3O7S2

Chemical Name: N-{3-[2-(2-{3-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]propoxy}ethoxy)ethoxy]propyl}-5-(1,2-dithiolan-3-yl)pentanamide

Smiles: O=C(CCN1C(=O)C=CC1=O)NCCCOCCOCCOCCCNC(=O)CCCCC1CCSS1

InChiKey: CMMJPHOERVZWAY-UHFFFAOYSA-N

InChi: InChI=1S/C25H41N3O7S2/c29-22(6-2-1-5-21-10-20-36-37-21)26-11-3-14-33-16-18-35-19-17-34-15-4-12-27-23(30)9-13-28-24(31)7-8-25(28)32/h7-8,21H,1-6,9-20H2,(H,26,29)(H,27,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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