JMJD7-IN-1 - CAS# 311316-96-8


Catalog No. Size PriceQuantity
M16512-C Contact sales@xcessbio.com for quotation $100

Description

JMJD7-IN-1 is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM. JMJD7-IN-1 shows good inhibitory activity against cells expressing a high level of JMJD7.

Product information

CAS Number: 311316-96-8

Molecular Weight: 363.15

Formula: C16H8Cl2N2O4

Chemical Name: 5-nitroquinolin-8-yl 2,4-dichlorobenzoate

Smiles: [O-][N+](=O)C1=CC=C(OC(=O)C2=CC=C(Cl)C=C2Cl)C2=NC=CC=C12

InChiKey: YKPUGYXWOBGQLL-UHFFFAOYSA-N

InChi: InChI=1S/C16H8Cl2N2O4/c17-9-3-4-10(12(18)8-9)16(21)24-14-6-5-13(20(22)23)11-2-1-7-19-15(11)14/h1-8H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

JMJD7-IN-1 (0.1-1000 μM) dose-dependently inhibits the activity of JMJD7, with an IC50 of 6.62 μM. JMJD7-IN-1 efficiently binds to JMJD7, with an IC50 of 3.80 μM. JMJD7-IN-1 (72 h) inhibits the growth of T-47d, SK-BR-3, Jurkat and Hela cells, with IC50s of 9.40 μM, 13.26 μM, 15.03 μM and 16.14 μM, respectively.

Products are for research use only. Not for human use.

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