Description
Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM.
Product information
CAS Number: 1269726-67-1
Molecular Weight: 415.24
Formula: C19H15Cl2F3N2O
Chemical Name: 1-[2-(2,4-dichlorophenyl)-2-{[4-(trifluoromethyl)phenyl]methoxy}ethyl]-1H-imidazole
Smiles: FC(F)(F)C1=CC=C(COC(CN2C=NC=C2)C2=CC=C(Cl)C=C2Cl)C=C1
InChiKey: FUAHXHWSMYFWGE-UHFFFAOYSA-N
InChi: InChI=1S/C19H15Cl2F3N2O/c20-15-5-6-16(17(21)9-15)18(10-26-8-7-25-12-26)27-11-13-1-3-14(4-2-13)19(22,23)24/h1-9,12,18H,10-11H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 ± 0.3 μM.
In Vivo:
Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 %.
Products are for research use only. Not for human use.
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