Description
Cav 2.2 blocker 2 is a Cav2.2 calcium channel blocker extracted from patent WO2017046581A1, compound 1. Cav 2.2 blocker 2 can reverses hyperalgesia associated with an injury or inflammation in conjunction with the opioid.
Product information
CAS Number: 1204535-44-3
Molecular Weight: 463.90
Formula: C19H21ClF3N3O3S
Chemical Name: (2S)-2-methyl-1-(2-methylpyridine-3-carbonyl)-4-[4-(trifluoromethyl)benzenesulfonyl]piperazine hydrochloride
Smiles: Cl.CC1=NC=CC=C1C(=O)N1CCN(C[C@@H]1C)S(=O)(=O)C1C=CC(=CC=1)C(F)(F)F
InChiKey: BPYXATSRTWDGML-ZOWNYOTGSA-N
InChi: InChI=1S/C19H20F3N3O3S.ClH/c1-13-12-24(10-11-25(13)18(26)17-4-3-9-23-14(17)2)29(27,28)16-7-5-15(6-8-16)19(20,21)22;/h3-9,13H,10-12H2,1-2H3;1H/t13-;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (233.95 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Cav 2.2 blocker 2 (compound 1) (1-10 mg/kg; p.o.) in conjunction with Morphine (0.3 mg/kg) reverses the complete freunds adjuvant (CFA) induced hyperalgesia in rats.
Products are for research use only. Not for human use.
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