Description
Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL.
Product information
CAS Number: 12626-17-4
Molecular Weight: 479.57
Formula: C27H33N3O5
Chemical Name: (1R,2S,12S,15S)-1,2-dihydroxy-7-methoxy-10-(3-methylbut-2-en-1-yl)-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0³,¹¹.0⁴,⁹.0¹⁵,¹⁹]icosa-3(11),4,6,8-tetraene-14,20-dione
Smiles: CC(C)=C[C@H]1C2=C([C@H](O)[C@@]3(O)C(=O)N4CCC[C@H]4C(=O)N31)C1=CC=C(C=C1N2CC=C(C)C)OC
InChiKey: WEIYXEFMCIRZHC-MWGWWEMPSA-N
InChi: InChI=1S/C27H33N3O5/c1-15(2)10-12-28-20-14-17(35-5)8-9-18(20)22-23(28)21(13-16(3)4)30-25(32)19-7-6-11-29(19)26(33)27(30,34)24(22)31/h8-10,13-14,19,21,24,31,34H,6-7,11-12H2,1-5H3/t19-,21-,24-,27+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Fumitremorgin B (3 or 4 days) inhibits the proliferation of U937 and PC3 cells, with IC50 of 14.12 and 43.36 μM, respectively. Fumitremorgin B exhibits antifungal activities against the phytopathogenic fungi B. cinerea, A. solani, A. alternata, C. gloeosporioides, F. solani, F. oxysporum f. sp. niveum, F. oxysporum f. sp. vasinfectum, and G. saubinettii, with MICs of 6.25-50 μg/mL.
Products are for research use only. Not for human use.
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