SBI-477


Catalog No. Size PriceQuantity
M17093-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

SBI-477 is an insulin signaling inhibitor that deactivates the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). SBI-477 inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes.

Product information

CAS Number: 781628-99-7

Molecular Weight: 483.54

Formula: C24H25N3O6S

Chemical Name: 3-methoxy-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-[2-(morpholin-4-yl)-2-oxoethoxy]benzamide

Smiles: COC1C=CC(=CC=1)C1=CSC(NC(=O)C2=CC(OC)=C(C=C2)OCC(=O)N2CCOCC2)=N1

InChiKey: SJPVXFZDWAIFFT-UHFFFAOYSA-N

InChi: InChI=1S/C24H25N3O6S/c1-30-18-6-3-16(4-7-18)19-15-34-24(25-19)26-23(29)17-5-8-20(21(13-17)31-2)33-14-22(28)27-9-11-32-12-10-27/h3-8,13,15H,9-12,14H2,1-2H3,(H,25,26,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). DMSO: 97 mg/mL(200.6 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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