D-erythro-MAPP - CAS# 143492-38-0


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M17518-C Contact sales@xcessbio.com for quotation $100

Description

D-erythro-MAPP (D-e-MAPP) is a ceramidase inhibitor, with an IC50 of 1-5 μM in vitro.

Product information

CAS Number: 143492-38-0

Molecular Weight: 361.56

Formula: C23H39NO2

Chemical Name: N-[(1S, 2R)-1-hydroxy-1-phenylpropan-2-yl]tetradecanamide

Smiles: C[C@@H](NC(=O)CCCCCCCCCCCCC)[C@@H](O)C1C=CC=CC=1

InChiKey: YLAZEWZHIRBZDA-NFBKMPQASA-N

InChi: InChI=1S/C23H39NO2/c1-3-4-5-6-7-8-9-10-11-12-16-19-22(25)24-20(2)23(26)21-17-14-13-15-18-21/h13-15,17-18,20,23,26H,3-12,16,19H2,1-2H3,(H,24,25)/t20-,23-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

D-erythro-MAPP (D-e-MAPP) reduces the viability of MCF-7 cells in a dose-dependent manner with IC50 value of 4.4 μM, and 15.6 μM, respectively. D-erythro-MAPP (D-e-MAPP) induces G0/G1 arrest in cell cycle progression resulting in growth suppression.

Products are for research use only. Not for human use.

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