Crocin IV


Catalog No. Size PriceQuantity
M17608-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Crocin IV (Dicrocin), a crocetin glycoside, is a carotenoid pigment. Crocin IV has potent antioxidant activity.

Product information

CAS Number: 57710-64-2

Molecular Weight: 652.68

Formula: C32H44O14

Chemical Name: bis[(2S, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (2E, 4E, 6E, 8E, 10E, 12E, 14E)-2, 6, 11, 15-tetramethylhexadeca-2, 4, 6, 8, 10, 12, 14-heptaenedioate

Smiles: C/C(/C=C/C=C(\C)/C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)=C\C=C\C=C(/C)\C=C\C=C(/C)\C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChiKey: QBZWPZHDUZGTLS-IIDMIUPYSA-N

InChi: InChI=1S/C32H44O14/c1-17(11-7-13-19(3)29(41)45-31-27(39)25(37)23(35)21(15-33)43-31)9-5-6-10-18(2)12-8-14-20(4)30(42)46-32-28(40)26(38)24(36)22(16-34)44-32/h5-14,21-28,31-40H,15-16H2,1-4H3/b6-5+,11-7+,12-8+,17-9+,18-10+,19-13+,20-14+/t21-,22-,23-,24-,25+,26+,27-,28-,31+,32+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Crocin IV (Dicrocin; 10 μM; 24 hours) has little or no effect on the prolongation of cell survival in PC12 cell. Crocin IV enhances γ-GCS mRNA expression in serum-deprived and hypoxic PC12 cells. Measurements of cell viability, peroxidized membrane lipids and caspase-3 activity showed that the rank order of the neuroprotective potency at a concentration of 10 μM is crocin>tricrocin>dicrocin and picrocrocin (the latter two crocins had a little or no potency).

Products are for research use only. Not for human use.

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