Ga(III) protoporphyrin IX


Catalog No. Size PriceQuantity
M17627-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Ga(III)protoporphyrin-IX is a model for the key interporphyrin interactions in malaria pigment. Ga(III)protoporphyrin-IX acts as a potent antibacterial against gram-negative, gram-positive, and acid-fast bacteria. Ga(III)protoporphyrin-IX is readily soluble in methanol (MeOH). Ga(III)protoporphyrin IX are as malarial pigment analogues for drug development and as potential antibacterial agents.

Product information

CAS Number: 222556-71-0

Molecular Weight: 629.36

Formula: C34H31GaN4O4

Chemical Name: gallium(III) hydrogen 2, 18-bis(2-carboxylatoethyl)-3, 8, 13, 17-tetramethyl-7, 12-divinylporphyrin-21, 23-diide

Smiles: [H+].[Ga+3].CC1=C(C=C)C2=CC3=NC(=CC4[N-]C(C=C5N=C(C=C1[N-]2)C(C)=C5CCC([O-])=O)=C(CCC([O-])=O)C=4C)C(C=C)=C3C

InChiKey: ZRDMJAGESDWCMV-RGGAHWMASA-K

InChi: InChI=1S/C34H34N4O4.Ga/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Ga(III)protoporphyrin-IX has also been shown to bind to heme containing proteins and enzymes when it is included in the cellular growth medium of the Grampositive bacteria Enterococcus faecalis which does not depend on heme for cell growth. Ga(III)protoporphyrin-IX has shown to be a suitable mimic of heme and has potential applications in heme replacement/substitution.

Products are for research use only. Not for human use.

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