Description
Ga(III)protoporphyrin-IX is a model for the key interporphyrin interactions in malaria pigment. Ga(III)protoporphyrin-IX acts as a potent antibacterial against gram-negative, gram-positive, and acid-fast bacteria. Ga(III)protoporphyrin-IX is readily soluble in methanol (MeOH). Ga(III)protoporphyrin IX are as malarial pigment analogues for drug development and as potential antibacterial agents.
Product information
CAS Number: 222556-71-0
Molecular Weight: 629.36
Formula: C34H31GaN4O4
Chemical Name: gallium(III) hydrogen 2, 18-bis(2-carboxylatoethyl)-3, 8, 13, 17-tetramethyl-7, 12-divinylporphyrin-21, 23-diide
Smiles: [H+].[Ga+3].CC1=C(C=C)C2=CC3=NC(=CC4[N-]C(C=C5N=C(C=C1[N-]2)C(C)=C5CCC([O-])=O)=C(CCC([O-])=O)C=4C)C(C=C)=C3C
InChiKey: ZRDMJAGESDWCMV-RGGAHWMASA-K
InChi: InChI=1S/C34H34N4O4.Ga/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Ga(III)protoporphyrin-IX has also been shown to bind to heme containing proteins and enzymes when it is included in the cellular growth medium of the Grampositive bacteria Enterococcus faecalis which does not depend on heme for cell growth. Ga(III)protoporphyrin-IX has shown to be a suitable mimic of heme and has potential applications in heme replacement/substitution.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.