Description
Bosutinib D8 (SKI-606 D8) is a deuterium labeled Bosutinib. Bosutinib is a dual Src/Abl inhibitor with IC50s of 1.2 nM and 1 nM, respectively.
Product information
Molecular Weight: 538.50
Formula: C26H29Cl2N5O3
Chemical Name: 4-((2, 4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl-2, 2, 3, 3, 5, 5, 6, 6-d8)propoxy)quinoline-3-carbonitrile
Smiles: [2H]C1([2H])N(CCCOC2C=C3N=CC(C#N)=C(NC4=CC(OC)=C(Cl)C=C4Cl)C3=CC=2OC)C([2H])([2H])C([2H])([2H])N(C)C1([2H])[2H]
InChiKey: UBPYILGKFZZVDX-COMRDEPKSA-N
InChi: InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)/i6D2,7D2,8D2,9D2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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