Description
EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells.
Product information
Molecular Weight: 223.29
Formula: C10H13N3OS
Chemical Name: 7-(ethylsulfanyl)-N,N-dimethyl-2,1,3-benzoxadiazol-4-amine
Smiles: CCSC1=CC=C(C2=NON=C12)N(C)C
InChiKey: AEMFWHVETFLRKQ-UHFFFAOYSA-N
InChi: InChI=1S/C10H13N3OS/c1-4-15-8-6-5-7(13(2)3)9-10(8)12-14-11-9/h5-6H,4H2,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
EtS-DMAB can selectively detect hypochlorous acid (HOCl) over other reactive oxygen species in aqueous solution with a large stokes shift (∼170 nm). It turns out that oxidation of the thioether to the corresponding sulfoxide accounts for the turn-on fluorescence.
Products are for research use only. Not for human use.
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