ELOVL6-IN-2


Catalog No. Size PriceQuantity
M17857-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

ELOVL6-IN-2 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-2 inhibits mouse ELOVL6 activities, with an IC50 value of 34 nM.

Product information

CAS Number: 1067647-43-1

Molecular Weight: 579.49

Formula: C28H23F6N3O4

Chemical Name: 6, 6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluoromethoxy)phenyl]-2, 3-dihydro-1H-pyrazol-4-yl}-1-phenyl-3-(trifluoromethyl)-2, 3, 4, 5, 6, 7-hexahydro-1H-indole-2, 4-dione

Smiles: CC1(C)CC(=O)C2=C(C1)N(C1C=CC=CC=1)C(=O)C2(C1C(=O)N(NC=1C)C1C=CC(=CC=1)OC(F)(F)F)C(F)(F)F

InChiKey: XLEVMSDNWOWFNX-UHFFFAOYSA-N

InChi: InChI=1S/C28H23F6N3O4/c1-15-21(23(39)37(35-15)17-9-11-18(12-10-17)41-28(32,33)34)26(27(29,30)31)22-19(13-25(2,3)14-20(22)38)36(24(26)40)16-7-5-4-6-8-16/h4-12,35H,13-14H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (172.57 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

ELOVL6-IN-2 (0.1~1mg/kg; p.o.; 2 hours) potently and dose-proportionally suppresses the elongation index in the liver. ELOVL6-IN-2 (10mg/kg; p.o.; 2 hours) demonstrates highly liver penetrable. ELOVL6-IN-2 (1mg/kg; p.o.; 2~24 hours) exhibits sustained plasma exposure.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed