Description
Sotorasib (AMG-510) racemate is the racemate of Sotorasib (AMG-510). AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.
Product information
CAS Number: 2252403-56-6
Molecular Weight: 560.59
Formula: C30H30F2N6O3
Chemical Name: 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(propan-2-yl)pyridin-3-yl]-4-[2-methyl-4-(prop-2-enoyl)piperazin-1-yl]-1H, 2H-pyrido[2, 3-d]pyrimidin-2-one
Smiles: CC1=CC=NC(C(C)C)=C1N1C2=NC(C3=C(O)C=CC=C3F)=C(F)C=C2C(=NC1=O)N1CCN(C[C@@H]1C)C(=O)C=C
InChiKey: NXQKSXLFSAEQCZ-SFHVURJKSA-N
InChi: InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8-7-9-22(24)39)34-29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1,12-13,15H2,2-5H3/t18-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 3.85 mg/mL (6.87 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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