Description
L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively.
Product information
CAS Number: 1030017-51-6
Molecular Weight: 375.84
Formula: C19H15ClFNO2S
Chemical Name: 2-{9-[(4-chlorophenyl)sulfanyl]-6-fluoro-1H,2H,3H-benzo[b]pyrrolizin-1-yl}acetic acid
Smiles: OC(=O)CC1CCN2C1=C(SC1C=CC(Cl)=CC=1)C1C=CC(F)=CC2=1
InChiKey: GSBAVONRPNJJOH-UHFFFAOYSA-N
InChi: InChI=1S/C19H15ClFNO2S/c20-12-1-4-14(5-2-12)25-19-15-6-3-13(21)10-16(15)22-8-7-11(18(19)22)9-17(23)24/h1-6,10-11H,7-9H2,(H,23,24)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 6 mg/mL (15.96 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
L 888607 Racemate (compound 3) maintains a modest binding affinity for the DP1 receptor (Ki = 132 nM) and is actually 8-fold more potent on the TP receptor (Ki = 17 nM).
Products are for research use only. Not for human use.
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