Etersalate


Catalog No. Size PriceQuantity
M17973-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Etersalate inhibits platelet function and decreases thromboxane A2 (TXA2) levels.

Product information

CAS Number: 62992-61-4

Molecular Weight: 357.36

Formula: C19H19NO6

Chemical Name: 2-(4-acetamidophenoxy)ethyl 2-(acetyloxy)benzoate

Smiles: CC(=O)OC1=CC=CC=C1C(=O)OCCOC1C=CC(=CC=1)NC(C)=O

InChiKey: PXBFSRVXEKCBFP-UHFFFAOYSA-N

InChi: InChI=1S/C19H19NO6/c1-13(21)20-15-7-9-16(10-8-15)24-11-12-25-19(23)17-5-3-4-6-18(17)26-14(2)22/h3-10H,11-12H2,1-2H3,(H,20,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Ex vivo antiplatelet properties of Etersalate and its effects on serum thromboxane A2 (TXA2) levels and prostaglandin I2 (PGI2) generation are studied in human volunteers at two levels of oral dosing. Etersalate inhibits at the lower dosage platelet function and decreased TXA2 levels, but PGI2 generation from rat aortic rings is stimulated when incubated with plasma from Etersalate-treated donors. Blood coagulation parameters remain within normal values. Etersalate administration can act on platelet arachidonate metabolism at a different level than that of the cyclooxygenase pathway.

Products are for research use only. Not for human use.

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