Description
GR 103691 is a potent, selective dopamine D3 receptor antagonist with a Ki value of 0.4 nM. GR 103691 shows more than 100-fold selectivity for human dopamine human (h)D3 over hD4 and hD1 sites.
Product information
CAS Number: 162408-66-4
Molecular Weight: 485.62
Formula: C30H35N3O3
Chemical Name: 4'-acetyl-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-[1,1'-biphenyl]-4-carboxamide
Smiles: CC(=O)C1C=CC(=CC=1)C1C=CC(=CC=1)C(=O)NCCCCN1CCN(CC1)C1=CC=CC=C1OC
InChiKey: JARNORYOPMINDY-UHFFFAOYSA-N
InChi: InChI=1S/C30H35N3O3/c1-23(34)24-9-11-25(12-10-24)26-13-15-27(16-14-26)30(35)31-17-5-6-18-32-19-21-33(22-20-32)28-7-3-4-8-29(28)36-2/h3-4,7-16H,5-6,17-22H2,1-2H3,(H,31,35)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 25 mg/mL (51.48 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
GR 103691 shows marked affinity for serotonin1A (5-HT1A) receptors (Ki of 5.8 nM) and α-1 adrenoceptors (Ki of 12.6 nM).
Products are for research use only. Not for human use.
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