Description
GSK2200150A, identified by high-throughput screening (HTS) campaign, is an anti-tuberculosis (TB) agent.
Product information
CAS Number: 1443138-53-1
Molecular Weight: 357.47
Formula: C20H23NO3S
Chemical Name: 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran]
Smiles: C(C1C=C2OCCOC2=CC=1)N1CCC2(CC1)OCCC1SC=CC2=1
InChiKey: NCRPMBWORFWNGT-UHFFFAOYSA-N
InChi: InChI=1S/C20H23NO3S/c1-2-17-18(23-11-10-22-17)13-15(1)14-21-7-5-20(6-8-21)16-4-12-25-19(16)3-9-24-20/h1-2,4,12-13H,3,5-11,14H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 65 mg/mL (181.83 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
GSK2200150A is a novel antimycobacterial agent against Mycobacterium tuberculosis.The activities of GSK2200150A containing the spirocycle core are determined against the virulent M.tuberculosis strain (H37Rv) with MIC of 0.38 μM.
Products are for research use only. Not for human use.
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