Bifluranol


Catalog No. Size PriceQuantity
M18171-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bifluranol (BX341) is an anti-androgen.

Product information

CAS Number: 34633-34-6

Molecular Weight: 292.32

Formula: C17H18F2O2

Chemical Name: 2-fluoro-4-[(2S,3R)-2-(3-fluoro-4-hydroxyphenyl)pentan-3-yl]phenol

Smiles: C[C@@H]([C@@H](CC)C1=CC(F)=C(O)C=C1)C1=CC(F)=C(O)C=C1

InChiKey: RDVXUHOSYIBGBT-ZWNOBZJWSA-N

InChi: InChI=1S/C17H18F2O2/c1-3-13(12-5-7-17(21)15(19)9-12)10(2)11-4-6-16(20)14(18)8-11/h4-10,13,20-21H,3H2,1-2H3/t10-,13-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

The absorption, distribution and excretion of Bifluranol have been studied in mouse, rat, ferret and dog; Bifluranol is readily absorbed following oral administration, but blood concentrations of Bifluranol are low due to hepatic uptake and biliary excretion. After intravenous administration of [3H]Bifluranol to rats (200 μg/kg) and ferrets (60 μg/kg) the blood concentrations of 3H decreases rapidly for the first 2 to 3 h, with the decrease being more rapid in females ( 18 min for rat, 30 min for ferret) than males (1.0 h for rat, 1.4 h for ferret). This is followed by a much slower decline (40 h for rat, 20 h for ferret) to concentrations at 96 h of less than 15 ng Bifluranol equivalents mL-1 (rat) or 1 ng Bifluranol equivalents mL-1 (ferret).

Products are for research use only. Not for human use.

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