IDO-IN-8


Catalog No. Size PriceQuantity
M18208-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.

Product information

CAS Number: 1402837-77-7

Molecular Weight: 316.37

Formula: C18H21FN2O2

Chemical Name: (1S,4r)-4-[(1S)-2-[(5R)-6-fluoro-5H-imidazo[4,3-a]isoindol-5-yl]-1-hydroxyethyl]cyclohexan-1-ol

Smiles: O[C@@H]1CC[C@H](CC1)[C@@H](O)C[C@@H]1C2C(F)=CC=CC=2C2=CN=CN21

InChiKey: YGACXVRLDHEXKY-RYPCIWMOSA-N

InChi: InChI=1S/C18H21FN2O2/c19-14-3-1-2-13-16-9-20-10-21(16)15(18(13)14)8-17(23)11-4-6-12(22)7-5-11/h1-3,9-12,15,17,22-23H,4-8H2/t11-,12-,15-,17+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

IDO-IN-8 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-8 at which inhibits 50% of enzymatic activity using recombinant human IDO).

Products are for research use only. Not for human use.

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