DR4485 hydrochloride


Catalog No. Size PriceQuantity
M18266-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14).

Product information

CAS Number: 402942-53-4

Molecular Weight: 491.88

Formula: C26H29Cl3N2O

Chemical Name: 9-chloro-4-{4-[4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridin-1-yl]butyl}-2-azatricyclo[6.3.1.0⁴,¹²]dodeca-1(12),2,8,10-tetraen-3-ol hydrochloride

Smiles: Cl.OC1=NC2C=CC(Cl)=C3CCCC1(CCCCN1CC=C(CC1)C1=CC=C(Cl)C=C1)C3=2

InChiKey: QAERYGXKDZHTFR-UHFFFAOYSA-N

InChi: InChI=1S/C26H28Cl2N2O.ClH/c27-20-7-5-18(6-8-20)19-11-16-30(17-12-19)15-2-1-13-26-14-3-4-21-22(28)9-10-23(24(21)26)29-25(26)31;/h5-11H,1-4,12-17H2,(H,29,31);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

DR4485 (MZ54 WT cells; 6 µM or 8 µM) hydrochloride induces autophagy as well as cell death that is diminished by KO of ATG5 and ATG7.

Products are for research use only. Not for human use.

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