FGFR4-IN-1


Catalog No. Size PriceQuantity
M18309-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

FGFR4-IN-1 is a potent inhibiotr of FGFR4 with IC50 of 0.7 nM.

Product information

CAS Number: 1708971-72-5

Molecular Weight: 493.52

Formula: C24H27N7O5

Chemical Name: N-{5-cyano-4-[(2-methoxyethyl)amino]pyridin-2-yl}-7-formyl-6-[(3-oxomorpholin-4-yl)methyl]-1,2,3,4-tetrahydro-1,8-naphthyridine-1-carboxamide

Smiles: COCCNC1=CC(NC(=O)N2CCCC3C=C(CN4CCOCC4=O)C(C=O)=NC2=3)=NC=C1C#N

InChiKey: ZTYSXMGILYNNJX-UHFFFAOYSA-N

InChi: InChI=1S/C24H27N7O5/c1-35-7-4-26-19-10-21(27-12-18(19)11-25)29-24(34)31-5-2-3-16-9-17(20(14-32)28-23(16)31)13-30-6-8-36-15-22(30)33/h9-10,12,14H,2-8,13,15H2,1H3,(H2,26,27,29,34)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 6.4 mg/mL (12.97 mM; Need warming).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

FGFR4-IN-1 significantly inhibits the proliferation of HuH-7 hepatocellular carcinoma cells with IC50 of 7.8 nM.

Products are for research use only. Not for human use.

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