Becampanel


Catalog No. Size PriceQuantity
M18667-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent.

Product information

CAS Number: 188696-80-2

Molecular Weight: 330.19

Formula: C10H11N4O7P

Chemical Name: ({[(7-nitro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}methyl)phosphonic acid

Smiles: [O-][N+](=O)C1=CC(CNCP(O)(O)=O)=C2NC(=O)C(=O)NC2=C1

InChiKey: ABFMMCZFKUIJGQ-UHFFFAOYSA-N

InChi: InChI=1S/C10H11N4O7P/c15-9-10(16)13-8-5(3-11-4-22(19,20)21)1-6(14(17)18)2-7(8)12-9/h1-2,11H,3-4H2,(H,12,15)(H,13,16)(H2,19,20,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Becampanel is negative in a mouse lymphoma tk assay, which includes a 24 h treatment without S9. A weak micronucleus induction in vitro is found at the highest concentrations tested in V79 cells with S9.

In Vivo:

Becampanel is negative in the following in vivo studies, which includes the maximum tolerated doses of 320 mg/kg in mice and 2000 mg/kg in rats. Becampanel has no genotoxic potential in vivo.

Products are for research use only. Not for human use.

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