5-ALA benzyl ester hydrochloride


Catalog No. Size PriceQuantity
M18773-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines.

Product information

CAS Number: 163271-32-7

Molecular Weight: 257.71

Formula: C12H16ClNO3

Chemical Name: benzyl 5-amino-4-oxopentanoate hydrochloride

Smiles: Cl.NCC(=O)CCC(=O)OCC1C=CC=CC=1

InChiKey: GHMCTRQKEALPCK-UHFFFAOYSA-N

InChi: InChI=1S/C12H15NO3.ClH/c13-8-11(14)6-7-12(15)16-9-10-4-2-1-3-5-10;/h1-5H,6-9,13H2;1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (970.08 mM; Need ultrasonic). H2O : 100 mg/mL (388.03 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) (0.6-0.12 mM; 3 h) induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines SW480.

In Vivo:

Reducing the dose of 5-ALA benzyl ester hydrochloride (31 mg/kg; i.v. ; 1 hours) results in a dose-dependent reduction in tumour porphyrin levels.

Products are for research use only. Not for human use.

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