4-PPBP maleate


Catalog No. Size PriceQuantity
M18822-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

4-PPBP maleate is a potent σ 1 receptor ligand and agonist. 4-PPBP maleate is a non-competitive, selective NR1a/2B NMDA receptors (expressed in Xenopus oocytes) antagonist. 4-PPBP maleate provides neuroprotection.

Product information

CAS Number: 201216-39-9

Molecular Weight: 409.52

Formula: C25H31NO4

Chemical Name: (2E)-but-2-enedioic acid; 4-phenyl-1-(4-phenylbutyl)piperidine

Smiles: OC(=O)/C=C/C(O)=O.C(CCCN1CCC(CC1)C1C=CC=CC=1)C1C=CC=CC=1

InChiKey: OASPNIMFGJVLES-WLHGVMLRSA-N

InChi: InChI=1S/C21H27N.C4H4O4/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20;5-3(6)1-2-4(7)8/h1-6,9-10,12-13,21H,7-8,11,14-18H2;1-2H,(H,5,6)(H,7,8)/b;2-1+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

4-PPBP maleate elicits ERK1/2 phosphorylation in primary neurons.

In Vivo:

4-PPBP maleate (1 μmol/kg; i.v.) decreases brain injury after transient focal ischemia in rats.

Products are for research use only. Not for human use.

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