Description
ICI 211965 (ZM-211965) is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor.
Product information
CAS Number: 129424-08-4
Molecular Weight: 389.51
Formula: C24H23NO2S
Chemical Name: 2-(1-methoxy-1-{3-[(naphthalen-2-yl)methoxy]phenyl}propyl)-1,3-thiazole
Smiles: COC(CC)(C1=NC=CS1)C1C=C(C=CC=1)OCC1C=C2C=CC=CC2=CC=1
InChiKey: XYRDHZXSQUWVCD-UHFFFAOYSA-N
InChi: InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-13-14-28-23)21-9-6-10-22(16-21)27-17-18-11-12-19-7-4-5-8-20(19)15-18/h4-16H,3,17H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ICI 211965 (ZM-211965) is a selective and orally potent 5-Lipoxygenase (5-LPO) inhibitor. ICI 211965 reduces the leakage of lactate dehydrogenase (LD) and lipid peroxidation at concentrations related to its antioxidative effect and not to its 5-1ipoxygenase-inhibiting effect.
Products are for research use only. Not for human use.
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