Description
CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM.
Product information
CAS Number: 912367-45-4
Molecular Weight: 366.48
Formula: C20H22N4OS
Chemical Name: 4-{[(2R,3S)-2-methylpiperidin-3-yl]amino}-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Smiles: C[C@H]1NCCC[C@@H]1NC1N=CC(C(N)=O)=C2SC(=CC2=1)C1C=CC=CC=1
InChiKey: LMQOZGSVTQQPFU-WBMJQRKESA-N
InChi: InChI=1S/C20H22N4OS/c1-12-16(8-5-9-22-12)24-20-14-10-17(13-6-3-2-4-7-13)26-18(14)15(11-23-20)19(21)25/h2-4,6-7,10-12,16,22H,5,8-9H2,1H3,(H2,21,25)(H,23,24)/t12-,16+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM, which is a potential cancer therapeutic that can be utilized for enhancing the efficacy of DNA damaging agents.
Products are for research use only. Not for human use.
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