DMP-543


Catalog No. Size PriceQuantity
M19189-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer.

Product information

CAS Number: 160588-45-4

Molecular Weight: 412.43

Formula: C26H18F2N2O

Chemical Name: 10,10-bis[(2-fluoropyridin-4-yl)methyl]-9,10-dihydroanthracen-9-one

Smiles: O=C1C2=CC=CC=C2C(CC2=CC(F)=NC=C2)(CC2=CC(F)=NC=C2)C2=CC=CC=C21

InChiKey: MUJBUUDUXGDXLW-UHFFFAOYSA-N

InChi: InChI=1S/C26H18F2N2O/c27-23-13-17(9-11-29-23)15-26(16-18-10-12-30-24(28)14-18)21-7-3-1-5-19(21)25(31)20-6-2-4-8-22(20)26/h1-14H,15-16H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (242.47 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

DMP-543 enhances [3H]ACh release from rat brain slices, with an EC50 of 700 nM.

Products are for research use only. Not for human use.

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